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Product Description
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Biovision | P1461 | Human CellExp™ 4-1BB Ligand/TNFSF9, Human recombinant DataSheet
Biomolecule/Target :
Synonyms: 4‑1BB Ligand, TNFSF9, CD137L
Alternates names: 4‑1BB Ligand, TNFSF9, CD137L
Taglines: A transmembrane cytokine
NCBI Gene ID #: 8744
NCBI Gene Symbol: EPS15
Gene Source: Human
Accession #: P41273-1
Recombinant: True
Source: HEK 293 cells
Purity by SDS-PAGE: >95%
Assay: SDS-PAGE
Purity:
Assay #2:
Endotoxin Level: Less than 1.0 EU per ug by the LAL method.
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.3 kDa. The protein migrates as 25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Concentration:
Appearance: Dry powder
Physical form description: Lyophilized
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Amino acid sequence: Ala 50 - Glu 254
Handling: Centrifuge the vial prior to opening.
Usage:
