Product Description
phospho-NF1 (Ser2515) Polyclonal Antibody | BS65916 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat,Horse,Rabbit,
Application: IHC-P,
Application Range: IHC-P=1:100-500
Background: Neurofibromin is a product of the tumor suppressor gene, Neurofibromatosis type I. Neurofibromin is known to have GTPase activity that modulates the ras pathway. The absence of or alteration of the neurofibromin protein may lead to Neurofibromatosis disease. This protein has not been purified, therefore, most of the information regarding this protein has been deduced from homology analysis of its gene sequence.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: phospho-NF1 (Ser2515) Polyclonal Antibody detects endogenous levels of NF1 protein only when phosphorylated at Ser2515.
Molecular Weight: 147/319kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NF1 (phospho S2515) ; NF1 (phospho Ser2515) ; p-NF1 (S2515) ; DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS.
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human NF1 around the phosphorylation site of Ser2515:QT (p-S) PR
Conjugate: Unconjugated
Modification: Phosphorylation
Purification & Purity: affinity purified by Protein A
Pathway: