Product Description
FMOD polyclonal Antibody | BS8168 | Bioworld
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200
Background: Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromodulin, and Lumican mediate extracellular matrix organization and are binding partners of TGFbeta. Fibromodulin is a collagen-binding Keratan sulphate proteoglycan that influences adhesion processes of connective tissue, and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. The core proteins of SLRPs consist of a central region of leucine-rich repeats flanked by disulfide-linkages of the terminal domains. Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon, and ligament. The human Fibromodulin gene maps to chromosome 1q32 and encodes a 376 amino acid protein.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FMOD polyclonal Antibody detects endogenous levels of FMOD protein.
Molecular Weight: ~ 43 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Fibromodulin; FM; Collagen-binding 59 kDa protein; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin; FMOD; FM; SLRR2E
Immunogen: Recombinant full length Human FMOD.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: