Why is Bovine Serum used in Cell Culture ?

Why is Bovine Serum used in Cell Culture ?

Posted by Djoumana Ounas on 9th Dec 2019

Fetal Bovine Serum is used for Cell Cultured by laboratories as a culture Medium additive.

that helps creating the right environment for cells to grow. Moreover, the fetal bovine serum is the most widely used serum that has high quality of carrier proteins, hormones and different other macromolecular proteins that helps in in-vitro cell culture of normal human and mammal cells as well as cell lines. More specifically these serum additive helps in the rapid growth of embryonic cells that are being transferred to the DMEM culture medium.

Apart from this these fetal bovine serums are being used from many years in order to clone various animal cells. Fetal calf serum is also being widely use in different cell culture applications due to its large variety of growth factors, cytokines and nutriments and also due to low level of antibodies present in it that makes it more effective and efficient. Inactivated bovine serum albumin is used in certain research applications and tests that need inactivation of antibodies and treated by heat inactivation in which the serum is particularly exposed to 56’C temperature for 30 minutes under different controlled conditions. Also Serum albumin of other species like Mouse, rabbit, hamster, horse can be used.