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![CD86 Antibody [2D10] (Biotin)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576736/814642/porsci_lo__79508.1648973713__13539.1649092253.png?c=2 "CD86 Antibody [2D10] (Biotin)")
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Product Description
CD86 Antibody [2D10] (Biotin) | 99-095 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: Mouse B cell lymphoma cell line 5C2
Research Area: Innate Immunity
Tested Application: IHC-P, IHC-Fr, ICC, Flow
Application: CD86 Antibody [2D10] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, and separation assays.
Specificiy: CD86
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [2D10]
Isotype: IgG2b
Conjugate: Biotin
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: B7-2, B70, Ly-58
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1) , CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4) . It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
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