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Product Description
Human CD33/Siglec-3 protein, His tag (Animal-Free) | PRP2032 | Abbkine
Product Category: Cytology
Application: Cytokines
Product Type: Cytokines (Animal-Free)
Sequence: Amino acid sequence derived from human CD33 protein (AAA51948, Met1-His259) was expressed with a polyhistidine tag at the C-terminus.
Activity: N/A
protein Lenght: The recombinant human CD33/Siglec-3 protein consists of 248 amino acids and predicts a molecular mass of 27.3 kD.The apparent molecular mass of the human CD33 is approximately 40-55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Preparation: HEK 293 Cells
Purity: >95% as determined by SDS-PAGE
Formulation: 0.22 µm filtered protein solution is in PBS, pH 7.4.
Kit Component: N/A
Features & Benefits : Endotoxin: <0.1 EU per μg of the protein as determined by the LAL method.
Molecular Weight: 27.3 kDa
Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD33/Siglec-3 protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.
Storage Conditions: Lyophilized Human CD33/Siglec-3 protein, His tag (Animal-Free) should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.111% HSA or BSA) . Please prevent freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature.
Background: The transmembrane protein CD33 is a sialic acid-binding immunoglobulin-like lectin that mediate the cell-cell interaction and inhibiting normal functions of immune cells. CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism of the innate immune system. In the brain, CD33 is mainly expressed on microglial cells.
Alternative Names: CD33 Molecule;SIGLEC3;Sialic Acid-Binding Ig-Like Lectin 3;Myeloid Cell Surface Antigen CD33;CD33 Antigen (Gp67) ;SIGLEC-3;Gp67;Sialic Acid Binding Ig-Like Lectin 3;CD33 Molecule Transcript 3;CD33 Antigen
Search Names: CD33 Molecule;SIGLEC3;Sialic Acid-Binding Ig-Like Lectin 3;Myeloid Cell Surface Antigen CD33;CD33 Antigen (Gp67) ;SIGLEC-3;Gp67;Sialic Acid Binding Ig-Like Lectin 3;CD33 Molecule Transcript 3;CD33 Antigen
Tag: CD33/Siglec-3
