The ISTYPES stands for International System of Typographic Picture Education which showing the presentation of social, biological and historical connections. ISOTYPES in mammals divided into five main classes IgA, IgD, IgE, IgG and IgM they are classed by their heavy chain they contain like alpha, delta, epsilon, gamma or mu. ISOTYPES should not be used to determine compensation levels or the negative population. Antibody needs the ISOTYPES because it reflects the maturation of a B Cell which are Fc receptor of molecules.

A mechanism that cause the production of antibodies to change the stage from lgM to other antibody ISOTYPOES like lgE,lgA or lgG that have defined the roles of the immune systems. lgM is the most abundant circulating antibody that consist 80% of total antibodies.

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