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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Biovision | MK-2461 | B3359

    Biovision | MK-2461 | B3359

    MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met. MK-2461 inhibits in vitro phosphorylation of a peptide substrate recognized by wild-type or oncogenic c-Met kinases (N1100Y, Y1230C, Y1230H, Y1235D, and M1250T) with IC50...

    $250.00 - $810.00
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  • Tetrahydroxanthohumol

    Biovision | Tetrahydroxanthohumol | B3340

    Tetrahydroxanthohumol (TXN) is a synthetic derivative of the flavonoid antioxidant Xanthohumol (Cat. No. 2258). TXN attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ. A peroxisome proliferator activated receptor gamma (PPARγ)...

    $194.00 - $592.00
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  • Ofloxacin

    Biovision | Ofloxacin | B3339

    Ofloxacin (Hoe-280) is a fluoroquinolone antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. The primary mechanism of action is...

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  • AFN-1252

    Biovision | AFN-1252 | B3338

    AFN-1252 is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI). Inhibits all clinical isolates of Staphylococcus aureus (n = 502) and Staphylococcus epidermidis (n = 51) tested, including methicillin (meticillin)-resistant isolates, at...

    $253.00 - $820.00
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  • Yoda-1

    Biovision | Yoda-1 | B3335

    Yoda -1 is a synthetic small molecule that acts as an agonist for both human and mouse Piezo1. Characterization of Yoda1 in artificial droplet lipid bilayers shows that Yoda1 activates purified Piezo1 channels in the absence of other cellular components...

    $288.00 - $966.00
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  • OATD-01

    Biovision | OATD-01 | B3334

    OATD-01 is a small molecule inhibitor of acidic mammalian chitinase (AMCase) (IC50 = 9 nM) and chitotriosidase (CHIT1) (IC50 = 26 nM). OATD-01 displays robust anti-fibrotic activity in multiple animal modelsOATD-01 is a small molecule inhibitor of acidic...

    $159.00 - $451.00
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  • BC-1618

    Biovision | BC-1618 | B3333

    BC-1618 is a potent Fbxo48 inhibitory compound that stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). Fbxo48 and was much more potent than metformin in increasing Ampk function. BC1618 promotes...

    $206.00 - $639.00
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  • BMS-813160

    Biovision | BMS-813160 | B3332

    BMS-813160 is a potent antagonist of chemokine receptor 2 (CCR2) and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays). BMS-813160 specifically binds and prevents the activation of both CCR2 and CCR5. BMS 813160 inhibits...

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  • BMS-191011

    Biovision | BMS-191011 | B3331

    BMS-191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1). Acts as a neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke).BMS-191011 is a...

    $217.00 - $685.00
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  • Lesinurad sodium

    Biovision | Lesinurad sodium | B3330

    Lesinurad (RDEA-594) sodium is a selective uric acid reabsorption inhibitor (SURI). Lesinurad sodium also inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively...

    $171.00 - $498.00
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  • K-777

    Biovision | K-777 | B3329

    K-777 is a potent and irreversible cysteine protease inhibitor. Also acts as a potent cysteine protease cruzain (cruzipain) inhibitor. Active against Trypanosoma cruzi the causative agent of Chagas' disease, a parasitic infection which is a leading cause...

    $171.00 - $498.00
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  • BAY-2402234

    Biovision | BAY-2402234 | B3328

    BAY-2402234 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = 1.2 nM). It induces upregulation of the cell differentiation marker CD11b in MOLM-13 and HEL acute myeloid leukemia (AML) cells (EC50s = 3.16 and 0.96 nM, respectively) and...

    $217.00 - $685.00
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  • TAS-109

    Biovision | TAS-109 | B3327

    TAS-109 is a novel deoxycitidine analog that inhibits DNA polymerase resulting in S-phase arrest, while prolonged exposure to TAS-109 at low concentration causes DNA fragmentation, G2/M phase arrest and apoptosis. TAS-109 displays activity in tumor...

    $276.00 - $908.00
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  • GSK-3484862

    Biovision | GSK-3484862 | B3326

    GSK3484862 (GSKMI-714) is a selective, reversible, non-covalent DNMT1 (DNA Methyltransferase 1) inhibitor. Potently inhibits the methyltransferase activity of DNMT1, but not DNMT family members DNMT3A or DNMT3B.GSK3484862 (GSKMI-714) is a selective,...

    $217.00 - $685.00
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  • SZL-P1-41

    Biovision | SZL-P1-41 | B3325

    SZL P1-41 is a specific Skp2 inhibitor that binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. Also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. Suppresses the survival of cancer cells...

    $288.00 - $966.00
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  • SR-4370

    Biovision | SR-4370 | B3324

    SR-4370 is a potent and selective inhibitor of histone deacetylase 3 (HDAC3; IC50 = 6 nM). It displays selectivity for HDAC3 over HDAC1, -2, -6, and -8 (IC50s = 0.13, 0.58, 3.7, and 2.3 µM, respectively). SR-4370 suppresses AR signaling and in vivo...

    $194.00 - $592.00
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  • PF-06821497

    Biovision | PF-06821497 | B3323

    PF-06821497 is a potent and selective EZH2 (Enhancer of Zeste Homolog 2) inhibitor, inhibiting the activities of both wild-type (Ki = 0.3nM) and mutant (Y641N) (Ki < 0.1nM). Displays robust tumor growth inhibition.PF-06821497 is a potent and selective...

    $171.00 - $498.00
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  • JNJ-64619178

    Biovision | JNJ-64619178 | B3322

    JNJ-64619178 is a selective and pseudo-irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 of 0.14 nM). It inhibits the growth of various cancer cells in vitro and reduces tumor growth in non-small cell lung cancer (NSCLC) and small...

    $206.00 - $639.00
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  • GSK-3326595

    Biovision | GSK-3326595 | B3321

    GSK-3326595 is a potent and selective protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50 = 6.2 nM) that induces cell death in a broad range of solid and hematologic tumor cell lines. It also displays potent anti-tumor activity in vivo in animal...

    $194.00 - $592.00
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  • MRTX-849

    Biovision | MRTX-849 | B3320

    MRTX-849 is a potent, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. MRTX849 covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bound conformation, and...

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  • AMG-337

    Biovision | AMG-337 | B3317

    AMG-337 is a potent and selective inhibitor of c-Met kinase activity (IC50 = 1 nM) and adaptor protein Gab-1 phosphorylation, that subsequently blocks downstream PI3K and MAPK pathways. It has been shown to inhibit hepatocyte growth factor-mediated c-Met...

    $206.00 - $639.00
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  • Cimetidine

    Biovision | Cimetidine | B3315

    Cimetidine is a potent histamine H2 receptor antagonist (Ki = 0.6 μM). It also acts as an inverse agonist, inhibiting basal cAMP production in CHO cells expressing recombinant H2 receptors (IC50 = 1.2 μM). Cimetidine inhibits histamine-induced acid...

    $136.00 - $288.00
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  • GI254023X

    Biovision | GI254023X | B3314

    GI254023X is a potent and selective ADAM10 metalloprotease inhibitor that displays over 100-fold higher potency at ADAM10 compared to ADAM17. Blocks constitutive release of IL-6R, CX3CL1 and CXCL16 in cell-based cleavage experiments. Inhibits calcium...

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  • PF-3716556

    Biovision | PF-3716556 | B3313

    PF-3716556 is a selective H+,K+-ATPase inhibitor (pIC50 = 6 in human recombinant ion-leaky assays). Highly selective for H+,K+-ATPase in vitro; inhibits gastric acid secretion, displays no activity at Na+,K+-ATPase, used for the treatment of...

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  • Lansoprazole

    Biovision | Lansoprazole | B3312

    Lansoprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase. It inhibits K+ and H+ accumulation in gastric microsomes in a concentration-dependent manner (IC50s = 6.3 and 7.0 µM, respectively) and inhibits H+/K+-ATPase activity by...

    $136.00 - $288.00
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  • SCH-28080

    Biovision | SCH-28080 | B3311

    SCH-28080 is a potent H+, K+-ATPase inhibitor (IC50 = 20 nM); binds to the K+ recognition site and is competitive with respect to K+. Inhibits gastric acid secretion in vitro and in vivo.SCH-28080 is a potent H+, K+-ATPase inhibitor (IC50 = 20 nM); binds...

    $147.00 - $381.00
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  • DTP3

    Biovision | DTP3 | B3310

    DTP3 is a potent and selective GADD45β/MKK7 inhibitor, that inhibits cancer-selective NF-kB survival pathway. DTP3 specifically kills MM cells, ex vivo and in vivo, ablating MM xenografts in mice, with no apparent adverse effects, nor evident toxicity to...

    $253.00 - $820.00
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  • TPPU

    Biovision | TPPU | B3309

    TPPU is a potent, brain-permeable, soluble epoxide hydrolase (sEH) inhibitor (IC50 values are 1.1 and 2.1 nM for murine and human receptor, respectively). Inhibits MAPK and NF-κB signaling, as well as reducing ER stress and cell death in models of...

    $217.00 - $685.00
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  • Lanraplenib

    Biovision | Lanraplenib | B3307

    Lanraplenib is a potent and selective second generation SYK inhibitor (IC50=9.5 nM). Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Lanraplenib is a potent...

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  • Vericiguat

    Biovision | Vericiguat | B3306

    Vericiguat (BAY10-21189), is a potent and orally active sGC (Soluble Guanylate Cyclase) stimulator. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is implicated in the pathogenesis of chronic kidney disease...

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  • Lersivirine

    Biovision | Lersivirine | B3305

    Lersivirine is a non-nucleoside, next generation reverse transcriptase inhibitor (IC50 = 118 nM for the wild-type HIV-1 enzyme). It inhibits a panel of 14 single-point mutant HIV-1 reverse transcriptases with mean IC50 values within 10-fold of the...

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  • Vorapaxar

    Biovision | Vorapaxar | B3304

    Vorapaxar (SCH-530348) is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a...

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  • Rimegepant

    Biovision | Rimegepant | B3303

    Rimegepant is an oral antagonist of the calcitonin gene-related peptide (CGRP) receptor (Ki = 0.027 nM). It inhibits cAMP production stimulated by α-CGRP in SK-N-MC human neuroblastoma cells (IC50 = 0.14 nM). Romegepant has been approved by the U.S. FDA...

    $147.00 - $405.00
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  • XTT Sodium Salt

    Biovision | XTT Sodium Salt | B3302

    XTT sodium is a useful dye to measure cell proliferation, cytotoxicity, and apoptosis through colorimetric assay. XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by...

    $235.00 - $756.00
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  • Euphol

    Biovision | Euphol | B3301

    Euphol is a naturally occurring tetracyclic triterpene that displays anti-inflammatory action. Euphol produces anti-inflammatory effects by mediating NF-κB, down-regulation of tumor necrosis factor-α and cyclooxygenase-2 and reduced activation of protein...

    $159.00 - $451.00
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  • CSF1R-IN-1

    Biovision | CSF1R-IN-1 | B3300

    CSF1R-IN-1, is a potent CSF1R inhibitor (IC50 of 0.5 nM). CSF1R plays an important role in the recruitment and differentiation of tumor-associated macrophages (TAM).CSF1R-IN-1, is a potent CSF1R inhibitor (IC50 of 0.5 nM). CSF1R plays an important role...

    $253.00 - $820.00
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  • Flucytosine

    Biovision | Flucytosine | B3299

    Flucytosine, a fluorinated pyrimidine analog that displays antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. Flucytosine inhibits DNA and RNA synthesis and interferes with ribosomal...

    $136.00 - $288.00
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  • MYF-01-37

    Biovision | MYF-01-37 | B3298

    MYF-01-37 is a novel covalent inhibitor of TEAD (transcriptional enhanced associate domain) targeting Cys380 when incubated with the TEAD2 protein.MYF-01-37 is a novel covalent inhibitor of TEAD (transcriptional enhanced associate domain) targeting...

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  • Resazurin sodium

    Biovision | Resazurin sodium | B3296

    Resazurin is a blue fluorogenic dye used as a redox indicator in cell viability and proliferation assays for bacteria, yeast or mammalian cells. The blue form of the dye is irreversibly reduced by enzymes in viable cells to generate a highly...

    $147.00 - $358.00
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