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Product Description
Human IL-1β protein | PRP1019 | Abbkine
Product Category: Cytology
Application: Cytokines
Product Type: Cytokines
Sequence: Amino acid sequence derived from human IL-1 β (NP_000567.1) (Ala 117-Ser 269) was expressed.
Activity: N/A
protein Lenght: The recombinant human IL-1β consists of 154 amino acids and has a predicted molecular mass of 17 kDa.
Preparation: E. coli
Purity: >98 % as determined by SDS-PAGE
Formulation: Lyophilized from sterile PBS, pH 7.4.
Kit Component: N/A
Features & Benefits : Endotoxin: < 0.01 EU per μg of the protein as determined by the LAL method.
Molecular Weight: 17 kDa
Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human GM-CSF protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage Conditions: Lyophilized Human IL-1β proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.10% HSA or BSA) . Please prevent freeze-thaw cycles.
Shipping: The product is shipped at ambient temperature.
Background: Interleukin-1β (IL-1β or IL-1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1β is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . IL-1β is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS) . IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Alternative Names: IL-1; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B
Search Names: IL-1; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B
Tag: IL-1β
