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Product Description
ERK1 Mouse Monoclonal Antibody (5E9) | ABM40328 | Abbkine
Immunogen: Recombinant Protein of ERK1 of MAPK3
Product Category: Protein
Application: Protein General Reagents
Product Type: Primary Antibody
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: IHC-P, IF
Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200) .
Clonality: Monoclonal
Isotype: Mouse IgG1
Formulation: Liquid solution
Kit Component: N/A
Concentration: 1 mg/ml
Storage Buffer: PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Condition: Gel pack with blue ice.
Background: MAPK1 (mitogen-activated protein kinase 1) encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for MAPK1.
Alternative Names: MAPK3
Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
