Product Description
RO52 Polyclonal Antibody | ABP60223 | Abbkine
Immunogen: Synthesized peptide derived from part region of human RO52 protein at amino acid sequence of 140-220
Product Category: Protein
Application: Protein General Reagents
Product Type: Primary Antibody
Host: Rabbit
Reactivity: Human
Application: WB, ELISA
Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000) .
Clonality: Polyclonal
Isotype: Rabbit IgG
Formulation: Liquid solution
Kit Component: N/A
Concentration: 1 mg/ml
Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Condition: Gel pack with blue ice.
Background: TRIM21 encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for TRIM21 have been described but the full-length nature of only one has been determined.
Alternative Names: E3 ubiquitin-protein ligase TRIM21 ;52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; RING finger protein 81; RING-type E3 ubiquitin transferase TRIM21; Ro (SS-A) ; Sjoegren syndrome type A antigen; SS-A; Tripartite motif-containing protein 21
Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.