Product Description
Hirudin | Refludan | IMS01-134-330 | Agrisera
Immunogen: purified full length recombinant protein (Refludan®, Hoechst Marion Roussel Inc, )
Host: Chicken
Conjugation: N/A
Clonality: Polyclonal
Isotype: N/A
Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in 0.9% NaCl, 0.02% sodium azide.
Format: Liquid
Tested Application: Total, purified IgY
Related Products: Secondary antibodies
Recommended Dilutions: 1 : 1000 (ELISA), 1 : 1000 (WB)
Molecular weight: 7 kDa
Confirmed Reactivity: Hirudin
Predicted Reactivity: Hirudo medicinalis
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Additional Information: Reactiv against purified hirudine; no reactivity against normal human plasma in ELISA
Background: Hirudin (P01050) is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII, by forming irreversible, noncovalent 1:1 complexes with alpha-thrombin. Hirudin is a 65 amino acid polypeptide, 7 kDa protein, naturally originating from the medical leech Hirudo medicinalis. It is a very potent thrombin inhibitor. Antibody binding to hirudin inhibits the interaction with alpha-thrombin.
Reconstitution: N/A
Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
TAIR Nnumbre: N/A
Category: Immunology
Research Area: Immunology