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Product Description
BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly thro?gh activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.
Biovision | 3672 | Bin1 Antibody DataSheet
Antibody Target: Bin1
Target Alternative Name: BIN1 , AMPH2 , amphiphysin-like , mgC10367 , DKFZp547F068 , AMPHL , SH3P9
Tag Line:
Category: Bcl-2
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat
Immunogen Sequence: Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1
Accession #: BC065160
Gene ID: 30948
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 30 µg (0.2 mg/ml) immunoaffinity purified rabbit anti-Bin-1 polyclonal antibody in phosphate-buffered saline (PBS) containing 0.1% BSA, 30% glycerol, and 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot
Positive Control:
Application And Usages: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested. The antibody recognizes ~65 kDa band in samples from human, mouse and rat origins. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples. Reactivity to other species has not been tested.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
