Euro
USD
British Pound
NULL
Product Description
FUS has been identified as a frequent translocation fusion partner of various transcription factors. FUS fusion genes have been shown to be associated with multiple tumor types which include liposarcoma, leukemia, histocytoma, and sarcoma. FUS is a multifunctional RNA-binding protein that associates with the nuclear matrix and Cajal bodies and appears to play a role in splicesome assembly, pre-mRNA splicing, DNA repair, transcriptional regulation and homologous recombination.
Biovision | 3771 | FUS Antibody DataSheet
Antibody Target: FUS
Target Alternative Name: FUS, Fusion (involved in t(12;16) in malignant liposarcoma), TLS, Translocated in liposarcoma protein, Pigpen, POMp75
Tag Line:
Category: FUS
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse
Immunogen Sequence: Synthetic peptide of human FUS
Accession #: P35637
Gene ID: 2521
Appearance: Colorless liquid
Form: Liquid
Concentration: N/A
Formulation: 100 µl purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
Purification: Affinity purified
Application: Western blot, Immunoprecipitation
Positive Control:
Application And Usages: Western blotting (1:500 1:2000) and Immunoprecipitation. HeLa cell lysate can be used as a positive control. However, the optimal concentrations should be determined individually. The antibody recognizes the FUS of human origin. Based on sequence identity, the antibody should also react with mouse samples. Reactivity to other species has not been tested.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
