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Product Description
Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the Rho-family small GTPases Rac and Cdc42. A serine/threonine kinase, PAK1 induces the formation of filopodia and lamellipodia in Swiss 3T3 cells. PAK1 inhibits myosin light chain kinase, and appears to play a role in the regulation of apoptosis by phosphorylating the death agonist Bad. Membrane targeting of PAK1 induces neurite outgrowth. PAK1 may also regulate NFkB activation.
Biovision | 3248 | PAK1 Antibody DataSheet
Antibody Target: PAK1
Target Alternative Name: PAK1, PAK-1, p21/Cdc42/Rac1-activated kinase 1. PAK alpha, Alpha-PAK , p65-PAK, mgC130001, mgC130000
Tag Line:
Category: PAK
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: Recombinant human PAK1
Accession #: Q13153
Gene ID: 5058
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2 mg/ml) Protein A affinity purified rabbit anti-PAK1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Purification: Affinity purified
Application: Western blot, Immunoprecipitation
Positive Control:
Application And Usages: Western blotting (0.5-4 µg/ml) and immunoprecipitation (10-20 µg/ml). However, the optimal conditions should be determined individually.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
