Product Description
Anti 8-OHdG monoclonal antibody
About 8-hydroxy-2'-deoxyguanosine (8-OHdG):
Reactive oxygen species (ROS) and oxidative stress may be crucial for development of various diseases such as diabetes, cancer, and may play an important role in the aging process. 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a product of oxidatively damaged DNA formed by hydroxy radical, singlet oxygen and direct photodynamic action. 8-OHdG can be detected in tissue, serum, urine and other biomaterials. Anti 8-OHdG monoclonal antibody (clone N45.1) is highly specific for DNA damage, not cross react with RNA oxidation products such as 8-hydroxy-guanine and 8-hydroxy-guanosine. Suitable for immunohistochemistry and ELISA.
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