Bcl-xL(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-xL(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
Tissue SpecificityBcl-xL(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-xL(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.