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Product Description
Rabbit Anti-Human IGF1R (pTyr1280) Polyclonal
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Size 100 µl
Target IGF1R (pTyr1280)
Conjugate APC/Cy7
Research Area Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Receptor Tyrosine Kinases | Cell Signaling | Growth Factors | Insulin and Insulin-like | Cancer | Neuroscience
Alternative Name IGFIRC Antibody, CD_antigen: CD221 Antibody, IGFIR Antibody, Soluble IGF1R variant 2 Antibody, CD221 Antibody, CD221 antigen Antibody, MGC142172 Antibody, Insulin-like growth factor 1 receptor beta chain Antibody, Insulin-like growth factor I recepto
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human IGF1R around the phosphorylation site of tyrosine 1280 (pTyr1280).
Immunogen Species Human
Applications WB
Host Rabbit
Isotype IgG
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:250-1:500); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of IGF1R only when phosphorylated at tyrosine 1280 (pTyr1280).
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Plasma Membrane, Cell Membrane, Single-Pass Type I Membrane Protein, Alphav-Beta3 Integrin-Igf-1-Igf1R Complex, Integral Component Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane, Receptor Complex
Tissue Specificity Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of
Accession Number NP_000866.1
Gene ID 3480
Swiss-Prot P08069
Field of Use For in vitro research use only.
