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Product Description
Rabbit Anti-Human MEK1 + MEK2 (pSer218/222) Polyclonal
Product Videos
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Size 100 µl
Target MEK1 + MEK2 (pSer218/222)
Conjugate Biotin
Research Area Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | MAPK Pathway
Alternative Name MAP kinase/Erk kinase 1 Antibody, MKK 1 Antibody, ERK activator kinase 1 Antibody, MAPK/ERK kinase 1 Antibody, MEK1 Antibody, MEKK1 Antibody, MKK1 Antibody, EC:2.7.12.2 Antibody, MAP2K1 Antibody, Dual specificity mitogen-activated protein kinase kina
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human MEK1 + MEK2 proteins around the phosphorylation sites of MEK1 at serine 218 (pSer218) and MEK2 at serine 222 (pSer222).
Immunogen Species Human
Applications WB
Host Rabbit
Isotype IgG
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:500-1500); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of MEK1 only when phosphorylated at serine 218 (pSer218) and MEK2 only when phosphorylated at serine 222 (pSer222). Detects ~ 45 kDa. Detects a band at ~45 kDa.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Cytoskeleton, Centrosome, Spindle Pole Body, Nucleus, Cytoplasm Membrane, Peripheral Membrane Protein, Cytoplasm, Membrane, Microtubule Organizing Center, Cytosol, Endoplasmic Reticulum, Endosome, Early Endosome, Late Endosome, Extracellular Exosome,
Tissue Specificity Widely expressed, with extremely low levels in brain.
Accession Number NP_002746.1/NP_109587.1
Gene ID 5604/5605
Swiss-Prot Q02750/P36507
Field of Use For in vitro research use only.
