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Product Description
Recombinant monoclonal antibody to EGFR domain III. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody h-R3 (Nimotuzumab). This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor
Biovision | A2004 | Anti-EGFR domain III (Nimotuzumab), Human IgG1, kappa Antibody DataSheet
Antibody Target: EGFR domain III
Target Alternative Name: ERBB; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor, Nimotuzumab
Tag Line: Protein A affinity purified recombinant monoclonal antibody to detect EGFR domain III expression in humans
Category: Biosimilars
Host: Recombinant
Isotype: Human IgG1, kappa
Species Reactivities: Human
Immunogen Sequence: Antibody generated by humanization of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors
Accession #: P00533
Gene ID: 1956
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: Supplied in PBS, pH 7.5
Purification: SOURCE: CHO cells
Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Block, Flow Cytometry
Positive Control:
Application And Usages: Block, FC, IHC
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: False
Immunocytochemistry Verified: False
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
![EGFR domain III Antibody [h-R3 (Nimotuzumab) ], Human IgG1](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/823717/1115301/porsci_lo__79508.1648973713__16731.1649084691__20868.1649235586__20251.1649248189__17734.1657533701.png?c=2 "EGFR domain III Antibody [h-R3 (Nimotuzumab) ], Human IgG1")
![EGFR domain III Antibody [h-R3 (Nimotuzumab) ], Rabbit IgG](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/823718/1115302/porsci_lo__79508.1648973713__16731.1649084691__20868.1649235586__20251.1649248189__10768.1657533702.png?c=2 "EGFR domain III Antibody [h-R3 (Nimotuzumab) ], Rabbit IgG")
