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Product Description
Glutathione peroxidase 4 (also known as GPX4) belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa.
Biovision | A2358 | Anti-Glutathione Peroxidase 4 Rabbit Monoclonal Antibody DataSheet
Antibody Target: Human Glutathione Peroxidase 4
Target Alternative Name: PHGPx; Selenoprotein GPX4; SnPHGPx; SnGPx; SMDS; GPX4
Tag Line: A rabbit monoclonal antibody targeting glutathione peroxidase 4, a protein that protects cells against oxidative damage
Category: GM-CSF
Host: Recombinant
Isotype: Rabbit IgG
Species Reactivities: Human Mouse Rat
Immunogen Sequence: Synthesized peptide derived from human gluthathione peroxidase 4
Accession #: P36969
Gene ID: 2879
Appearance: Liquid
Form: Rabbit monoclonal
Concentration:
Formulation: In PBS, pH 7.3, with 0.02% sodium azide, 0.05% BSA, 50% glycerol
Purification: Affinity Purification
Application: Western Blotting Immunoprecipitation (IP)
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: TRUE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
