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Product Description
Suppressor of tumorigenicity (ST2) belongs to the interleukin 1 family of receptors. It exists in two isoforms: soluble form (sST2) found circulating in the plasma and transmembrane receptor form (ST2L). This protein is expressed by cardiomyocytes and vascular endothelial cells. Binding of ST2L to its ligand IL-33, prevents hypertrophy of the myocardium and fibrosis. However, sST2 competes with ST2L to bind to IL-33 and upon binding its ligand, neutralizes the cardioprotective effects of IL-33 and ST2L. Elevated levels of sST2 are associated with ventricular remodeling, fibrosis and chronic heart failure.
Biovision | A2099 | Anti-ST2 Detection Antibody DataSheet
Antibody Target: ST2
Target Alternative Name:
Tag Line: Protein A purified mouse monoclonal antibody to detect ST2 in humans. This antibody is match-paired with Anti-ST2 Capture Antibody (Catalog# A2098) and can be used for applications such as ELISA, Lateral Flow and Chemiluminescence immunoassay (CLIA)
Category: Primary antibody
Host: Mouse
Isotype: IgG1
Species Reactivities: Human
Immunogen Sequence: Recombinant ST2
Accession #:
Gene ID:
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 10 mM PBS, pH 7.4, 0.02% Proclin 300
Purification: Protein A purified
Application: CLIA,Lateral Flow,ELISA
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: False
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: True
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
