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Product Description
Rabbit Anti-Human p53 (pSer315) Polyclonal
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Size 100 µl
Target p53 (pSer315)
Conjugate Alkaline Phosphatase
Research Area Cancer | Cell Cycle | p53 Pathway | Cancer | Tumor suppressors | Apoptosis | Cell Signaling | Epigenetics and Nuclear Signaling | DNA/RNA | DNA Damage and Repair
Alternative Name p53 tumor suppressor Antibody, Cellular tumor antigen p53 Antibody, Antigen NY-CO-13 Antibody, Phosphoprotein p53 Antibody, Tumor protein 53 Antibody, BCC7 Antibody, p53 Antibody, TP53 Antibody, P53_HUMAN Antibody, FLJ92943 Antibody, Mutant tumor pro
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human p53 around the phosphorylation site of serine 315 (pSer315).
Immunogen Species Human
Applications WB, IHC, IP, ELISA
Host Rabbit
Isotype N/A
Species Reactivity Human
Antibody Dilution WB (1:250-1:1000); IHC (1:50-1:150); IP (1-2.5 ug per mg lysate); ELISA (1:5000); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of p53 protein only when phosphorylated at serine 315 (pSer315). Detects a band at ~43 kDa.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Mitochondrion Matrix, Endoplasmic Reticulum, Nucleus Pml Body, Nucleus, Pml Body, Cytoplasm, Cytosol, Mitochondrion, Nuclear Chromatin, Nuclear Matrix, Nucleolus, Nucleoplasm, Intracellular, Protein Complex, Replication Fork
Tissue Specificity Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isofo
Accession Number NP_000537.3
Gene ID 7157
Swiss-Prot P04637
Field of Use For in vitro research use only.
