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Product Description
Rabbit Anti-Human PIK3R1 + PIK3R3 (pTyr467/199) Polyclonal
Product Videos
Custom Field
Size 100 µl
Target PIK3R1 + PIK3R3 (pTyr467/199)
Conjugate Unconjugated
Research Area Cell Signaling | Lipid Signaling | Lipid Kinases | Cancer | Immunology | Innate Immunity | TLR Signaling
Alternative Name PIK3R1 + PIK3R3 Antibody, PI3-kinase p85- alpha/ gamma Antibody, Phosphatidylinositol 3 kinase catalytic alpha polypeptide Antibody, PI3K Antibody, PIK3R1 Antibody, PI3K alpha Antibody, PtdIns 3 kinase regulatory subunit alpha Antibody, Phosphatidyli
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human PIK3R1 + PIK3R3 proteins around the phosphorylation site of PI3-kinase p85- alpha at tyrosine 467 (pTyr467) and PI3-kinase p85- gamma at tyrosine 199 (pTyr199).
Immunogen Species Human
Applications WB, ICC/IF
Host Rabbit
Isotype IgG
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:250-1:1000); ICC/IF (1:50-1:250); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of PI3-kinase p85- alpha only when phosphorylated at tyrosine 467 (pTyr467) and PI3-kinase p85- gamma only when phosphorylated at tyrosine 199 (pTyr199). Detects a band at ~55 kDa.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Cytosol, Endoplasmic Reticulum, Perinuclear Endoplasmic Reticulum Membrane, Nucleus, Plasma Membrane, Cell-Cell Junction, Cis-Golgi Network, Cytoplasm, Membrane, Phosphatidylinositol 3-Kinase Complex, Phosphatidylinositol 3-Kinase Complex Class Ia, P
Tissue Specificity Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level). Highest levels in brain and testis. Lower levels in adipose tissue, kidn
Accession Number NP_001229395.1/NP_001107644.1
Gene ID 5295/8503
Swiss-Prot P27986/Q92569
Field of Use For in vitro research use only.
