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Product Description
AMPK2 alpha2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (H mgCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart s?ggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Biovision | 3169 | AMPK?2 Antibody DataSheet
Antibody Target: AMPK?2
Target Alternative Name: 5'-AMP-activated protein kinase, catalytic subunit alpha-2, AMPK alpha-2 chain
Tag Line:
Category: AMPK
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse
Immunogen Sequence: KLH conjugated synthetic peptide between 476-507 amino acids from the C-terminal region of human AMPK alpha2.
Accession #: P54646
Gene ID: 5563
Appearance: Colorless liquid
Form: Liquid
Concentration: 1 mg/ml
Formulation: 100 µg (1 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification: Ammonium sulphate precipitated
Application: Western blot
Positive Control:
Application And Usages: The antibody can be used for and Western blotting (1:1000 dilution).
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
