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Product Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Biovision | A2047 | Anti-H3R8me2(asym) Antibody DataSheet
Antibody Target: H3R8me2(asym)
Target Alternative Name: H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3; HIST1H3A
Tag Line: Affinity purified rabbit polyclonal antibody to detect asymmetric dimethylation of Histone H3 at Arginine 8 in human, mouse and rat samples
Category: Antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: A synthetic methylated peptide targeting residues around Arginine 8 of human Histone H3
Accession #: Q16695
Gene ID: 8290
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification: Affinity purified
Application: Immunofluorescence (IF), Dot Blot, Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000, IF 1:50 - 1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: WB data verified using HeLa cells and H3 protein
Immunocytochemistry Verified: False
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: True
Flow Cytometry Verified: False
