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Product Description
Integrins are a family of cell surface transmembrane receptors, each consisting of an ? and a ? subunit that bind to extracellular matrix (ECM) proteins and cellular counter receptors and associate with the cytoskeleton. In mammals, 24 different integrins are generated through different combinations of 18 ? and 8 ? subunits. A number of human congenital disorders have been associated with defective integrin-mediated adhesion, including the blistering disorder junctional epidermolysis bullosa, the bleeding disorder Glanzmanns thrombastenia, leukocyte adhesion deficiency-I (?2 integrins in leukocytes) and leukocyte adhesion deficiency-III, nephrotic syndrome and interstitial lung disease and muscular dystrophy. Integrin alpha-V/beta-5 is a receptor for fibronectin and it recognizes the sequence R-G-D in its ligand.
Biovision | A1832 | Anti-Integrin ß-5 Antibody DataSheet
Antibody Target: Integrin ß-5
Target Alternative Name: Integrin ß 5, ITGB5, integrin subunit beta 5, integrin beta 5
Tag Line: Polyclonal antibody to detect Integrin ß-5 in human samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Human
Immunogen Sequence:
Accession #: P18084
Gene ID: 3693
Appearance: Liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
Purification: Affinity purified
Application:
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
