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Product Description
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Biovision | A2283 | Anti-Nectin-4 Antibody DataSheet
Antibody Target: Nectin-4
Target Alternative Name: LNIR, PRR4, EDSS1, PVRL4, nectin-4, NECTIN4, Nectin 4
Tag Line: Rabbit polyclonal antibody to detect Nectin-4 expression in human and mouse samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Human, Mouse
Immunogen Sequence: Recombinant Human Nectin-4 protein
Accession #: Q96NY8
Gene ID: 81607
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300
Purification: Protein G purified
Application: Immunohistochemistry (IHC) Immunofluorescence (IF) Western Blotting
Positive Control:
Application And Usages: WB (1:500-1:5000), IHC (1:200-1:500), IF (1:50-1:200)
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: TRUE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: TRUE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
