Product Description
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Biovision | A1916 | Anti-POT1 Antibody DataSheet
Antibody Target: POT1
Target Alternative Name: GLM9, HPOT1, CMM10, protection of telomeres 1, POT1
Tag Line: Affinity purified Rabbit polyclonal to PRAME
Category: Primary Antibodies
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2).
Accession #: Q9NUX5
Gene ID: 25913
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Application: Immunohistochemistry (IHC), Western Blotting
Positive Control:
Application And Usages: WB 1:200 - 1:2000, IHC 1:50 - 1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False