Product Description
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented thro?ghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), s?ggesting that BMP-4 may play a role in activation of the Smad pathway.
Biovision | 5674R | BMP-4 Antibody DataSheet
Antibody Target: BMP-4
Target Alternative Name: BMP4, BMP-4, BMP 4, bone morphogenetic protein 4, BMP2B, BMP2B1
Tag Line:
Category: BMP
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat, chicken, rabbit
Immunogen Sequence: Synthetic peptide surrounding amino acid 395 of human BMP-4
Accession #: P12644
Gene ID: 652
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: In phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
Purification: Affinity purified
Application: Western blot, Immunohistochemistry
Positive Control:
Application And Usages: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified