Product Description
Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-?. It is believed that decorin also plays a role in the cell cycle of chondrocytes.
Biovision | 3645R | Decorin Antibody DataSheet
Antibody Target: Decorin
Target Alternative Name: DCN , 125255 , P07585 , DSPG2 , PG40 , PGII , PGS2 , SLRR1B
Tag Line:
Category: Decorin
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat, rabbit, pig
Immunogen Sequence: Synthetic peptide surrounding amino acid 130 of human Decorin
Accession #: AAA52301.1
Gene ID: 1634
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Decorin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 25% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot, Immunohistochemistry
Positive Control: Western Blot: Jurkat cell lysate. IHC: skin tissue
Application And Usages: Western blotting (0.5-4 µg/ml), and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects ~22 kDa protein representing the Decorin fragment generated by digestion of human Decorin by MMP-3.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified