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Product Description
IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues.
Biovision | 5129 | IL-1 beta Antibody DataSheet
Antibody Target: IL-1b
Target Alternative Name: IL-1 beta, IL1 beta, IL 1 beta, Interluekin-1 beta, Interluekin 1 beta, interluekin
Tag Line:
Category: Interluekin
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Mouse
Immunogen Sequence: E. coli expressed murine IL-1?
Accession #: CAA28637
Gene ID: 52667
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-murine IL-1? polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5%BSA and 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot, Neutralization
Positive Control:
Application And Usages: Western blot analysis (0.5-4 µg/ml). Recombinant murine IL-1? (Cat.# 4129-10) can be used as a positive control. Per researchers feedback, the antibody can also be used in neutralization studies. However, the optimal conditions should be determined individually.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
