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Product Description
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Biovision | A1983 | Phospho IRF3 (S385) Antibody DataSheet
Antibody Target: Phospho IRF3 (Ser385)
Target Alternative Name: Interferon regulatory factor 3; IRF-3
Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of IRF3 at Ser385 in human, mouse, bovine and porcine samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Bovine, Porcine, Mouse, Human
Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human IRF3
Accession #: Q14653
Gene ID: 3661
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
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