Euro
USD
British Pound
NULL
Product Description
Survivin is a newly described apoptosis inhibitor that is expressed in many human cancers, but undetectable in terminally differentiated adult tissues. It has been shown that recombinant expression of Survivin conteracts apoptosis of B lymphocyte precursors deprived of interleukin 3 (IL-3), s?ggesting a potential role of Survivin in cancer therapy. Survivin interacts with the processed form of caspase-3 and inhibits its proteolytic activity.
Biovision | 3161 | Survivin Antibody DataSheet
Antibody Target: Survivin/TIAP
Target Alternative Name: BIRC5, IAP4 , API4, SVV , EPR-1
Tag Line:
Category: Surivivn
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: mouse
Immunogen Sequence: Synthetic peptide surrounding amino acids near the C-terminus of mouse survivin
Accession #: NP_033819
Gene ID: 11799
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2 mg/ml) affinity-purified rabbit anti-Survivin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification: Affinity purified
Application: Western blot
Positive Control:
Application And Usages: Western blot analysis (0.5 - 2 µg/ml). However, the optimal conditions should be determined individually. The immunoaffinity purified antibody detects an approximately 17 kDa mouse survivin by Western blot analysis. Mouse spleen tissue lysate can be used as positive control.
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
