Euro
USD
British Pound
NULL
Product Description
Macrophage Migration Inhibitory Factor (MIF) is a small secreted protein that can act as a pleiotropic pro-inflammatory cytokine as well as an enzyme. MIF pro-inflammatory activity can be initiated by signaling through CD74 and CD44, resulting in the secretion of TNF-α, IL-1, IL-6, IL-8, and various MMPs. The enzymatic activity of MIF is characterized by its ability to act as a tautomerase, capable of catalyzing the keto to enol isomerization of keto-phenylpyruvate and L-dopachrome. It appears as though MIF catalytic activity is dependent upon a trimeric configuration and a free N-terminal proline residue. Insect cell derived recombinant MIF is a 15 kDa protein containing 124 amino acid residues, including an N-terminal His-tag.
Product Videos
Custom Field
Size Various Sizes
Host No
Category Primary Antibodies
Gene name MIF
Clonality N/A
Clone N/A
concentration N/A
Contents Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Immunogen N/A
Form Solid; white powder or thin/invisible film
Purification N/A
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Reactivity N/A
Uniprot ID P14174
Note This product is available in other size, please contact us for more details
