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Product Description
Rabbit Anti-Human Tau (pSer422) Polyclonal
Product Videos
Size
Size 100 µl
Target Tau (pSer422)
Conjugate Unconjugated
Research Area Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Cell Signaling | Cytoskeleton | Microtubules | MT Associated Proteins | Neuroscience | Cell Markers | Neuron Markers | Axon Markers
Alternative Name Neurofibrillary tangle protein Antibody, MAPTL Antibody, Microtubule-associated protein tau Antibody, MTBT1 Antibody, Paired helical filament-tau Antibody, TAU Antibody, PHF-tau Antibody, MAPT Antibody
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human Tau around the phosphorylation site of serine 422 (pSer422).
Immunogen Species Human
Applications WB, IHC
Host Rabbit
Isotype IgG
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:250-1:1000); IHC (1:25-1:100); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of Tau only when phosphorylated at serine 422 (pSer422). Detects a band at ~80 kDa.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Cytoskeleton, Plasma Membrane, Cell Membrane, Peripheral Membrane Protein, Cytoplasmic Side, Cytosol, Axon, Microtubule, Microtubule Associated Complex, Tubulin Complex, Nucleus, Nuclear Periphery, Nuclear Speck, Axolemma Plasma Membrane, Axolemma, C
Tissue Specificity Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Accession Number NP_001116538.2
Gene ID 4137
Swiss-Prot P10636
Field of Use For in vitro research use only.
