Product Description
TSC2 is important in regulating cell proliferation and tumor development. Mutations in either the TSC1 or TSC2 tumor suppressor genes caused tuberous sclerosis complex (TSC), an autosomal dominant tumor syndrome. Tuberin is a product of the TSC2 tumor suppressor gene. Tuberin form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR).
Biovision | 3962 | TSC2 Antibody DataSheet
Antibody Target: TSC2
Target Alternative Name: anti-TSC2, Tuberin, Tuberous sclerosis 2 protein homolog
Tag Line:
Category: TSC2
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat
Immunogen Sequence: Synthetic peptide surrounding amino acid 1548 of rat TSC2
Accession #: P49816.
Gene ID: 24855
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 0.5 mg/ml affinity purified rabbit anti-TSC2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin
Purification: Affinity purified
Application: Western blot
Positive Control: Jurkat (Induced and Uninduced), Rat kidney, 3T3 cell lysates
Application And Usages: The antibody can be used for Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 3962BP-50) is available separately.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified