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Product Description
Biovision | AH10639 phosphate | B3342
Description: AH10639 phosphate is a novel inhibitor of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. AH10639 is significantly more potent and selective than pyrimethamine as an inhibitor of T. gondii dihydrofolate reductase (DHFR), with 50% inhibitory concentrations within the range of 0.018 to 0.033 µM.
Alternate Name/Synonyms: Antibiotic O-12 NSC-98771 AH 10639
Appearance: White to off-white solid
Formulation:
CAS Number: 84176-65-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₂H₁₈N₆ · H₃PO₄
Molecular Weight: 344.31
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >8 mg/ml Water
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tagbitor of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase
MDL Number: MFCD00012733
PubChem CID: 264001
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/264001
SMILES: CC(C)C1=NC2=C(N=C(N=C2N=C1C(C)C)N)N.OP(=O)(O)O
InChi: InChI=1S/C12H18N6.H3O4P/c1-5(2)7-8(6(3)4)16-11-9(15-7)10(13)17-12(14)18-11;1-5(2,3)4/h5-6H,1-4H3,(H4,13,14,16,17,18);(H3,1,2,3,4)
InChi Key: YNQBQYASRYRNRY-UHFFFAOYSA-N
Category: Biochemicals
