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Product Description
Biovision | Conophylline | B3383
Description: Conophylline is a naturally occurring plant-based vinca alkaloid that acts as a novel differentiation inducer for pancreatic β cells; can increase the numbers of ductal cells positive for pancreatic-duodenal-homeobox protein-1 and islet-like cell clusters. Conophylline suppresses pancreatic stellate cells and improves islet fibrosis in Goto-Kakizaki rats. It protects cells in cellular models of neurodegenerative diseases by inducing mTOR-independent autophagy.
Alternate Name/Synonyms: dimethyl (14S,25S)-14,25-diethyl-24,33-dihydroxy-31,32-dimethoxy-12,22-dioxa-1,9,18,29-tetrazadodecacyclo[23.13.1.16,9.02,23.03,21.05,19.06,17.011,13.028,36.030,35.036,39.014,40]tetraconta-3,5(19),16,20,27,30,32,34-octaene-16,27-dicarboxylate CS-0023949
Appearance: Solid
Formulation:
CAS Number: 142741-24-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
C₄₄H₅₀N₄O₁₀
Molecular Weight: 794.9
Cell-Permeable?: True
Purity: ≥98%
Solubilities: DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line: A biologically active natural product
MDL Number:
PubChem CID: 9853848
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/9853848
SMILES: CCC12CC(=C3C4(C1N(CC4)C5C(C2O)OC6=CC7=C(C=C56)C89CCN1C8C(CC(=C9N7)C(=O)OC)(C2C(C1)O2)CC)C1=CC(=C(C(=C1N3)OC)OC)O)C(=O)OC
InChi: InChI=1S/C44H50N4O10/c1-7-41-16-20(37(51)55-5)34-44(23-14-25(49)30(53-3)31(54-4)28(23)46-34)10-12-48(40(41)44)29-19-13-22-24(15-26(19)57-32(29)35(41)50)45-33-21(38(52)56-6)17-42(8-2)36-27(58-36)18-47-11-9-43(22,33)39(42)47/h13-15,27,29,32,35-36,39-40,45-46,49-50H,7-12,16-18H2,1-6H3
InChi Key: QZRIMAMDGWAHPQ-UHFFFAOYSA-N
Category: Biochemicals
