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Product Description
Biovision | Dexrazoxane | B3369
Description: Dexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. Dexrazoxane could chelate iron to decrease the generation of ROS, thus preventing ROS-induced cardiomyocyte apoptosis. Additionally, dexrazoxane is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury.
Alternate Name/Synonyms: 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione ICRF 187 NSC 169780
Appearance: White to light yellow to orange powder
Formulation:
CAS Number: 24584-09-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₁H₁₆N₄O₄
Molecular Weight: 268.27
Cell-Permeable?: True
Purity: ≥98% by titration
Solubilities: ~10 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handlinAvoid contact by all modes of exposure.
Tag Line: An intracellular iron chelator
MDL Number: MFCD00866449
PubChem CID: 71384
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/71384
SMILES: O=C(N1)CN(C[C@H](C)N2CC(NC(C2)=O)=O)CC1=O
InChi: InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChi Key: BMKDZUISNHGIBY-ZETCQYMHSA-N
Category: Biochemicals
