Euro
USD
British Pound
NULL
Product Description
Biovision | RA-9 | B3358
Description: RA-9 is a potent and selective proteasome-associated deubiquitinating enzymes (DUBs) inhibitor that displays favorable toxicity profile and anticancer activity. RA-9 blocks ubiquitin-dependent protein degradation without impacting 20S proteasome proteolytic activity. RA-9 selectively induces onset of apoptosis in ovarian cancer cell lines and primary cultures derived from donors.
Alternate Name/Synonyms: RA9 (3E,5E)-3,5-Bis[(4-nitrophenyl)methylene]-4-piperidinone
Appearance: Solid
Formulation:
CAS Number: 919091-63-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₉H₁₅N₃O₅
Molecular Weight: 365.34
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >4 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! by all modes of exposure.
Tag Line: An ubiquitin-proteasome system (UPS) inhibitor
MDL Number:
PubChem CID: 5469266
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/5469266
SMILES: C1C(=CC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(=CC3=CC=C(C=C3)[N+](=O)[O-])CN1
InChi: InChI=1S/C19H15N3O5/c23-19-15(9-13-1-5-17(6-2-13)21(24)25)11-20-12-16(19)10-14-3-7-18(8-4-14)22(26)27/h1-10,20H,11-12H2/b15-9+,16-10+
InChi Key: YUYPWAMLWZVHAE-KAVGSWPWSA-N
Category: Biochemicals
