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Product Description
Biovision | Anti-H3K18ac Polyclonal Antibody | A2359
Description: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called “histone code.” Acetylation of histone H3 is associated with active gene transcription, and acetylation of lysine 18 on histone H3 is associated with cancer prognosis.
Antibody Target: Human histone H3, acetylated at lysine 18
Target Alternative Name: H3 clustered histone 1; histone cluster 1 H3 Family Member A; Histone Cluster 1, H3a; Histone 1,; Histone H3.1; Histone H3/A; HIST1H3A
Tag Line: Polyclonal antibody that recognizes histone H3 acetylated at lysine 18, a putative tumor biomarker
Category: GM-CSF
Lot #:
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Clone#:
Species Reactivities: Mouse, Rat, Human
Immunogen Sequence: KLH-conjugated synthetic peptide surrounding N-terminal region of human histone H3 acetylated at lysine 18
Accession #: P68431
Gene Id: 8350
Form: Liquid
Appearance: Rabbit polyclonal
Concentration:
Formulation: Liquid in 0.42% potassium phosphate, 0.87% sodium chloride, pH 7.3, with 30% glycerol and 0.01% sodium azide
Purification: Immunogen affinity chromatography
Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Positive Control: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Application And Usages:
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: TRUE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: TRUE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
