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Product Description
Biovision | IL36A (Human) ELISA Kit | E5057-100
Description: Interleukin-36 alpha (IL36A) is a novel cytokine which belongs to the IL-1 family that is involved in the development of inflammatory diseases. Cells reported to express IL36A includes monocytes, B cells and T cells (1, 4). IL36A binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. IL36A levels are elevated in the serum and cerebrospinal fluid of patients with neuromyelitis optica spectrum disorder and correlate with disease activity. Thus, IL-36A act as a novel biomarker for monitoring disease severity in Neuromyelitis optica spectrum disorder. BioVision’s IL36A (Human) ELISA Kit is used for the quantitative detection of IL36A in serum, plasma, tissue homogenates and other biological fluids. It is based on the principle of sandwich ELISA. The capture antibody is pre-coated on 96-well plates. The standards, test mples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound conjugates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of IL36A in the sample.
Alternate Name: IL36A ELISA Kit; Interleukin-36 alpha ELISA Kit; FIL1 epsilon ELISA Kit; IL-1E ELISA Kit; IL1F6 ELISA Kit; FIL1 ELISA Kit; EPSILON ELISA Kit; FIL1E ELISA Kit; IL-1 epsilon ELISA Kit; IL1 ELISA Kit; EPSILON ELISA Kit; IL1E ELISA Kit; IL-1F6 ELISA Kit, FIL-1-epsilon ELISA Kit; interleukin 1 family ELISA Kit; member 6 ELISA Kit; epsilon ELISA Kit; interleukin 1 ELISA Kit; Interleukin 36 ELISA Kit; Alpha ELISA Kit; Interleukin-1 epsilon ELISA Kit; interleukin-1 family member 6 ELISA Kit; Interleukin-36 Alpha ELISA Kit
Tag Line: A highly sensitive sandwich ELISA kit for the quantitative measurement of IL36A
Summary: N/A
Detection Method: Absorbance is measured at 450 nm
Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids
Species Reactivity: Human
Applications: The ELISA kit is used for the quantitative detection of IL36A in serum, plasma, tissue homogenates and other biological fluids
Features & Benefits: Detection range: 0.156-10 ng/ml Sensitivity: 0.094 ng/ml Highly sensitive and specific Recovery Rate: 88-98% for serum, 85-103% for EDTA plasma and 85-104% for heparin plasma Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10%
