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Product Description
Biovision | K2042 | CD38 Activity Assay Kit (Fluorometric) DataSheet
Cluster of differentiation (CD38), also known as cyclic ADP ribose hydrolase is a multifunctional enzyme that catalyzes the synthesis and hydrolysis of Nicotinamide Adenine Dinucleotide (NAD) to Nicotinamide and ADP-ribose (ADPR). Additionally, CD38 generates second messengers, cyclic ADP-ribose (cADPR) using NAD as the substrate. Due to its role in NAD+ metabolism, the study of CD38 and its functions has been of great importance. CD38 has been implicated in regulating NAD+ metabolism, aging, and other diseased conditions including obesity, diabetes, heart disease, asthma, inflammation etc. Furthermore, CD38 is expressed by lymphoid, myeloid, red blood cells and platelets, the highest expression being found in plasma cells. High expression of CD38 by plasma cells makes CD38 an ideal target for targeted immunotherapy. BioVision’s CD38 Activity Assay Kit can be used to detect its activity in biological samples. The kit utilizes the ability of active CD38 to catalyze the conversion of a CD38 substrate to a fluorescent product (Ex/Em = 300/410 nm). This assay kit provides a rapid, simple and sensitive method to detect CD38 activity in a variety of sample types.
Alternate Name : CD38 Fluorometric Assay Kit,CD38,CD38 Activity Kit,CD38 Activity,CD38 Fluorometric Activity Assay,CD38 Activity Kit (Fluorometric),CD38 Activity Assay (Fluorometric),CD38 Activity Assay,Cluster of differentiation Assay Kit,CD38 Fluorometric Activity Kit,CD38 Fluorometric Activity Assay Kit,CD38 Assay Kit,CD38 Activity Assay Kit
Tag Line : To detect CD38 activity in biological samples
Summary : BioVision’s CD38 Activity Assay Kit can be used to detect its activity in biological samples. The kit utilizes the ability of active CD38 to catalyze the conversion of a CD38 substrate to a fluorescent product (Ex/Em = 300/410 nm). This assay kit provides a rapid, simple and sensitive method to detect CD38 activity in a variety of sample types.
Detection Method : Fluorescence (Ex/Em = 300/410 nm)
Sample Type : Cultured cells: Adherent or suspension cells. Highest expression of the protein was found in B-cells,Animal tissues: Soft tissues (i.e. Spleen)
Species Reactivity : All
Applications : Mechanistic studies of various cancers,Screening anti-cancer drugs,Measurement of CD38 activity in various tissues/cells
Features and Benefits : Sensitive method to detect CD38 activity in a variety of sample types,Rapid,Simple
