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Product Description
Biovision | Active EphB2 (Fc Tag), Human Recombinant | P1741
Description: Ephrin Type-B Receptor 2 (EphB2) is a transmembrane receptor tyrosine kinase glycoprotein that functions through bidirectional signaling between adjacent cells. EphB2 functions in axon guidance during development, and also regulates development of dendrites and formation of synapses. EphB2 also controls angiogenesis, movement and adhesion of certain cells, and may function as a tumor suppressor. Some mutations of EphB2 have been associated with prostate and brain cancer.
Biomolecule/Target:
Synonyms: EPH Receptor B2; Developmentally-Regulated Eph-Related Tyrosine Kinase; Tyrosine-Protein Kinase Receptor EPH-3; Tyrosine-Protein Kinase TYRO5
Alternates names:
Taglines: Involved in axon guidance during development
NCBI Gene ID #: 2048
NCBI Gene Symbol: Human
Accession #: P29323
Recombinant: True
Source: Human cells
Purity by SDS-PAGE: > 90% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.
Activity (Specifications/test method):
Biological activity: Immobilized Active EphB2 (Fc Tag) 2 μg/ml (100 μl/well) can bind Ephrin B2
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 78.5 kDa (predicted); 120 kDa (observed)
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions:
Amino acid sequence: Val 19 to Ser 482 with C-terminal Fc Tag
Handling: Centrifuge the vial prior to opening.
Usage:
