Product Description
Complement subcomponent C1q is composed of three polypeptide chains (A, B, and C). C1q associates with C1r and C1s to set up the first component of the serum complement system. Activation of the complement system is induced by interaction with the Fc regions of IgG or IgM antibodies within immune complexes, enhancing the ability of those antibodies and cells of the immune system to attack pathogens. C1q deficiency is associated with lupus and glomerulonephritis.
Biovision | P1721 | Complement Component C1q, Human Serum DataSheet
Biomolecule/Target :
Synonyms: C1q; C1QA; C1QB; C1QC; C1QG; Complement Component 1, Q Subcomponent
Alternates names: C1q; C1QA; C1QB; C1QC; C1QG; Complement Component 1, Q Subcomponent
Taglines: A critical component of the classical complement system
NCBI Gene ID #: Chain A - 712; Chain B - 713; Chain C - 714
NCBI Gene Symbol:
Gene Source: Human
Accession #: Chain A - P02745; Chain B - P02746; Chain C - P02747
Recombinant: False
Source: Human serum
Purity by SDS-PAGE: ≥ 96% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 410 kDa
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute to desired concentration in sterile deionized water.
Amino acid sequence:
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans