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Product Description
FAK2 is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. It regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. The protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity
Biovision | P1416 | FAK2/PYK2B, Human Recombinant DataSheet
Biomolecule/Target :
Synonyms: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta
Alternates names: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta
Taglines: Protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion.
NCBI Gene ID #: PTK2B
NCBI Gene Symbol: 2185
Gene Source: Human
Accession #: Q14289
Recombinant: False
Source: Baculovirus (sf9 Insect Cells)
Purity by SDS-PAGE: >95%
Assay: SDS-PAGE
Purity:
Assay #2:
Endotoxin Level:
Activity (Specifications/test method): >20 U/ug (nmol/min/ug) measured by using BioVision ADPsensorâ„¢ Universal Kinase Activity Assay Kit K212-100
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 76.2 kDa (contains N-His tag).
Concentration:
Appearance: Liquid
Physical form description:
Reconstitution Instructions:
Amino acid sequence: aa 360-1009
Handling: Centrifuge the vial prior to opening.
Usage:
