Euro
USD
British Pound
NULL
Product Description
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Biovision | P1126 | Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant DataSheet
Biomolecule/Target :Tnfsf18
Synonyms: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Alternates names: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Taglines: Tumor necrosis factor receptor superfamily member 18
NCBI Gene ID #: 240873
NCBI Gene Symbol: Tnfsf18
Gene Source: Mouse
Accession #: Q7TS55
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGE: > 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/ug
Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.
Biological activity: Immobilized Mouse GITR, His Tag at 10ug/mL (100 uL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 ug/mL.
Results: N/A
Binding Capacity: Immobilized Mouse GITR, His Tag at 10ug/mL (100 uL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 ug/mL.
Unit Definition: N/A
Molecular Weight: 41.4 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
Amino acid sequence: N/A
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
