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Product Description
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Biovision | P1419 | Human CellExp™ PVRIG, Fc Tag, Mouse recombinant DataSheet
Biomolecule/Target :
Synonyms: Poliovirus Receptor-related Immunoglobulin Domain-containing Protein, C7orf15, CD112R, CD112 receptor, MGC104322, MGC138297, MGC2463
Alternates names: Poliovirus Receptor-related Immunoglobulin Domain-containing Protein, C7orf15, CD112R, CD112 receptor, MGC104322, MGC138297, MGC2463
Taglines: acts as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
NCBI Gene ID #: 102640920
NCBI Gene Symbol:
Gene Source: Mouse
Accession #: A0A1B0GS01
Recombinant: False
Source: HEK 293 Cells
Purity by SDS-PAGE: >95%
Assay: SDS-PAGE
Purity:
Assay #2:
Endotoxin Level: Less than 1.0 EU per ug by the LAL method.
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.6 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Concentration:
Appearance: Lyophilized powder
Physical form description: Lyophilized powder
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 ug/ml.
Amino acid sequence:
Handling: Centrifuge the vial prior to opening.
Usage:
