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Product Description
Biovision | Human CellExp™ SARS-CoV-2 Spike RBD (L452R, T478K), Recombinant | P1744
Description: SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The mutations at L452R and T478K were identified in the SARS-CoV-2 Delta (particularly B.1.617.2) variants that originated in India.
Biomolecule/Target:
Synonyms: COVID-19 Spike RBD protein; 2019-nCoV Spike RBD protein; SARS-CoV-2 Mutant (L452R, T478K)
Alternates names:
Taglines: Recombinant Spike RBD mutant of the SARS-CoV-2 Delta variant
NCBI Gene ID #: 43740568
NCBI Gene Symbol: SARS-CoV-2
Accession #: P0DTC2
Recombinant: True
Source: HEK 293 cells
Purity by SDS-PAGE: ≥ 90% by SDS-PAGE
Assay:
Purity:
Assay #2:
Endotoxin Level: < 1 EU per 1 µg of protein as determined by LAL method
Activity (Specifications/test method):
Biological activity:
Results:
Binding Capacity:
Unit Definition:
Molecular Weight: 26.6 kDa (calculated); 33-35 kDa (observed due to glycosylation)
Concentration:
Appearance: Lyophilized protein
Physical form description: Lyophilized powder
Reconstitution Instructions:
Amino acid sequence:
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans
